Idiopathic dilated cardiomyopathy in children: Prognostic indicators
Idiopathic dilated cardiomyopathy in children: Prognostic indicators
Blog Article
Objective: Dilated cardiomyopathy (DCM) is a disorder featuring left ventricular dysfunction, heart failure, and a poor prognosis.The etiology is still unclear, despite diagnostic and therapeutic developments.This study was an evaluation of factors affecting the life span of a group of idiopathic DCM patients.Methods: A total of 79 patients from between October 2005 and October 2017 with a diagnosis of idiopathic DCM were evaluated retrospectively.Demographic characteristics, clinical information, left ventricular function, treatment, and follow-up of the patients were reviewed based on hospital Cutting / Serving Boards records.
Age, gender, parental consanguinity, cardiomegaly on telecardiography, reduced ejection fraction (EF) and shortening fraction (SF), degree of mitral regurgitation, and intracardiac thrombosis were determined to affect prognosis.Results: The patients were aged 20+-60 months, and the male/female ratio was 1.02/1.The patients most frequently presented with heart failure signs and symptoms (n=59, 74.7%).
The most common physical examination findings were a murmur (n=53, 67.1%) and tachycardia (n=48, 60.8%).Cardiomegaly was observed on telecardiography in 73.4% of the patients.
The EF and SF values were 35.7+-12.6% Deodorants and 17.3+-6.5%, respectively.
In all, 42 (53.2%) patients had mitral regurgitation of grade 2 or higher.The duration of follow-up was between 1 and 156 months (20+-34.9 months).Intracardiac thrombosis was detected in 4 (5.
1%) patients.The mortality rate was 36.7%.When the prognostic factors were compared according to survival time, it was determined that survival was reduced in cases of parental consanguinity, low EF, and cardiomegaly.Conclusion: The most important negative markers affecting the length of survival of DCM patients were parental consanguinity, cardiomegaly detected on telecardiography, and a reduced EF level.